What happens with a nutrient in your body?Pharmacokinetics

Pharmacokinetics refers to what happens to a substance, be it a nutrient or pharmaceutical, from the time it enters the body until it is completely excreted. Understanding and determining the pharmacokinetic profile is critically important during the development process of food supplements, as it leads to the optimization of absorption and bioavailability of the product. Pharmacokinetic profiles are routinely tested for all pharmaceuticals, yet very few producers of dietary supplements perform them. All Carocelle® products undergo this testing.

The main pharmacokinetic parameter to test is bioavailability. The test results indicate that Carocelle® products provide significantly higher concentrations of lutein & zeaxanthin, lycopene and resveratrol in the bloodstream in comparison to tested competitors with similar or even higher concentrations of actives.

  • Lutein & Zeaxanthin Blood Level – Maximum Level of Saturation [nM] [serum level change vs. baseline; 4 weeks of supplementation] [double-blind, randomized, Lycotec LTD., Cambridge, UK]
    Lutein & Zeaxanthin Blood Level – Maximum Level of Saturation [nM]

    * Concentration of lutein and zeaxanthin in serum measured by High Performance Liquid Chromatography

  • Resveratrol Blood Level [Cross-over study] [Lycotec LTD., Cambridge, UK]
    Resveratrol Blood Level
  • Lycopene Blood Level – Maximum Level of Saturation [mg/ml] [Serum level (vs. baseline: 4weeks of supplementation] [Lycotec Ltd., Cambridge, UK]
    Lycopene Blood Level – Maximum Level of Saturation [mg/ml]

    * Concentration of lutein and zeaxanthin in serum measured by High Performance Liquid Chromatography